Enantioselective synthesis of Anomala osakana pheromone and Janus integer pheromone: a flexible approach to chiral gamma-butyrolactones.
نویسندگان
چکیده
The enantioselective synthesis of Anomala osakana pheromone and Janus integer pheromone has been achieved without using any protecting groups. The synthesis involved using an asymmetric alkynylation to obtain gamma-hydroxy-alpha,beta-acetylenic esters with high ee (84%) and yields ( approximately 80%), followed by selective hydrogenation and lactonization in high overall yields (87% and 89%).
منابع مشابه
Catalytic, enantioselective synthesis of 1,2-anti-diols by asymmetric ring-opening/cross-metathesis.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 7 18 شماره
صفحات -
تاریخ انتشار 2009